In an intriguing scientific twist that really grabbed my attention, scientists have uncovered new insight on how the “type of calories” we eat – in this case protein vs. carbs – can have totally different effects on special brain cells involved in wakefulness and metabolism. Housed in our brains are specialized neurons called orexin cells. Orexin cells incite wakefulness and calorie burning. Previous research had shown that glucose, which comes from carb foods, can shut off the activity of orexin cells (which may be why we experience after-mealtime sluggishness).
In the study scientists sought to investigate how amino acids, which come from protein foods, affect the activity of orexin cells. They discovered that amino acids have the opposite effect of glucose and actually stimulate the orexin cells. Additionally, they found that amino acids can also block glucose from quieting the orexin cells. (Neuron, November 2011)
What this supports is that for optimal alertness and calorie burning, it is best to include some protein in all meals and snacks and to avoid those that are carb rich and protein poor.
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